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Prescription drugs that inhibit CYP2D6 exercise, such as paroxetine and quinidine, may well cause lowered clearance of oxycodone which may lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by eleven%, AUC by 13%, and t½ elim.Inquire your health care provider or pharm